Fresh Frozen Plasma Dose Calculator

The fresh frozen plasma dose calculator helps you to make quick decisions when you are faced with a bleeding patient. With this tool, you will find the plasma transfusion dose and the units needed at once. If you want to remind yourself about fresh frozen plasma uses, plasma donation, or what FFP is exactly, keep on reading!

We try our best to make our Omni Calculators as precise and reliable as possible. However, this tool can never replace professional medical advice, diagnosis, or treatment. All information on this website is for informational purposes only and is not intended to and should not serve as a substitute for medical consultation. Always seek the advice of a health provider.

Human blood consists of liquid and solid parts. The solid parts consist of cells – red blood cells, white blood cells, and platelets, while the liquid part is plasma alone. The liquid makes up about 55% of the whole blood volume, with cells being the rest (~45%). Blood plasma is mainly water but also contains essential proteins, such as coagulation factors, immunoglobulins, and albumins.

An average human has approximately 3 liters of plasma in their body. You can calculate it more precisely in the plasma volume calculator.

Plasma for medical uses comes from blood donations (or plasma donations). The blood is then centrifuged and split into red blood cell concentrate and platelet-rich plasma. After one more centrifugation, we get platelet concentrate and plasma. Freezing it within 8 hours after donation, we get a product called fresh frozen plasma – or FFP for short.

The calculator works in two ways: first, it tells you how much plasma your patient needs. Then, it counts the number of units you will need to meet this demand. Check the following fresh frozen plasma dose calculator's instructions if you have problems understanding it:

1. The first field to fill in is the patient weight. You can switch between units – no need to use the weight converter.

2. Then, choose the right dose for the patient – how many milliliters of FFP they should get per kilogram of body mass. A dose of 10-20 mL/kg increases the coagulation factor levels by 20-30%.

3. Choose the volume of your plasma unit.

4. The fresh frozen plasma dose calculator tells you right away how much of the product you should give to the patient – how much in total, and how many units you will need for that.

5. You can still modify the fields. The calculator will recalculate your result immediately.

Every blood product has its specific uses. As mentioned before, plasma has a high content of proteins. One of these proteins are coagulation factors, which play an irreplaceable role when it comes to keeping your blood within your vessels. When in shortage, you are extremely vulnerable to even minor injuries, as they may cause serious, life-threatening bleeding.

The indications for plasma transfusion include:

• Management of severe bleeding;
• Lack of coagulation factors, such as hemophilia;
• Not enough coagulation factors, like in hepatic insufficiency;
• Antidote to warfarin toxicity (when the calculated INR is too high);
• Thrombotic thrombocytopenic purpura (TTP); and
• Prevention of expected bleeding (e.g., before surgery).

The dose of FFP infusion depends on the patient's weight.

Despite blood plasma being most responsible for the blood volume, FFP infusion should never be given to treat volume expansion.

Human plasma can be obtained from either whole blood donation or a specific plasma donation.

During the exclusive plasma donation, blood is drawn from the donor, the plasma is separated from it, and the rest is pumped back into the donor's body. The whole process is called plasmapheresis. It usually takes longer than a regular blood donation.

How often can you donate plasma? Because you don't lose the solid part of your blood, your body can regenerate the plasma much faster. You can donate plasma twice in a seven-day period.

And don't worry about the quantities in the fresh frozen plasma dose calculator. The amount of the donated plasma is counted individually, based on your weight. You will donate only an amount that is safe and healthy for you.